First, note that $(D,A;E,B)=C(D,A;M,\infty)=-1$, so $ABDE$ is harmonic. This implies that the tangents at $B$ and $E$ to $\Gamma$ and $AD$ are concurrent. Hence it suffices to show that $AD$, the tangent at $B$, and $CN$ are concurrent.
Let $P$ be the intersection of $AD$ and $CN$. $BN=NA$ and the fact that $CB$ and $AP$ are parallel tell us $\bigtriangleup CBN \equiv \bigtriangleup PAN$, so $CB = PA$. This then gives $\bigtriangleup ABP \equiv \bigtriangleup BAC$ as $\angle{CBA}=\angle{PAB}$. Hence $\angle{PBA}=\angle{CAB}=\angle{BCA}$ as $BA=BC$. Therefore, $PB$ is tangent to $\Gamma$, so $P$ is our desired concurrence point.